segunda-feira, 5 de abril de 2010

Reunião Científica

Informações sobre a próxima reunião do grupo de estudos do LAFIEX-UFVJM

Data: 06 de abril de 2010, terça-feira;
Local: sala 04, prédio I, campus I, UFVJM.

17:30 – 18:00
Responsável: Fabrício de Paula (continuação)
Título: “Influência da imersão passiva em água no desempenho físico: participação dos componentes metabólicos e inflamatórios da recuperação pós-exercício”.

18:00 – 19:00
Responsável: Wellington Gomes
Título: “Imunologia e Envelhecimento”

Bibliografia sugerida:

1) The ageing immune system: is it ever too old to become young again?
Nature Reviews Immunology 9, 57-62 (January 2009)
Kenneth Dorshkind, Encarnacion Montecino-Rodriguez & Robert A. J. Signer

Ageing is accompanied by a decline in the function of the immune system, which increases susceptibility to infections and can decrease the quality of life. The ability to rejuvenate the ageing immune system would therefore be beneficial for elderly individuals and would decrease health-care costs for society. But is the immune system ever too old to become young again? We review here the promise of various approaches to rejuvenate the function of the immune system in the rapidly growing ageing population.

2) The aging of the immune system.
Transpl Int. 2009 Nov;22(11):1041-50. Epub 2009 Jul 16.
Weiskopf D, Weinberger B, Grubeck-Loebenstein B.

An age-related decline in immune functions, referred to as immunosenescence, is partially responsible for the increased prevalence and severity of infectious diseases, and the low efficacy of vaccination in elderly persons. Immunosenescence is characterized by a decrease in cell-mediated immune function as well as by reduced humoral immune responses. Age-dependent defects in T- and B-cell function coexist with age-related changes within the innate immune system. In this review, we discuss the mechanisms and consequences of age-associated immune alterations as well as their implications for health in old age.

3) CD4+ T cells and immunosenescence: a mini-review.
Gerontology. 2009;55(5):491-5. Epub 2009 Apr 23.
Maue AC, Haynes L.

Age-related declines in immune function are associated with reduced humoral responses following vaccination or infection. Central to this defect is a decline in naïve CD4+ T cell function. In this review, we discuss factors intrinsic and extrinsic to the CD4+ T cell compartment that affect host immunity and propose means by which deficient CD4+ T cell function can be fully restored in the aged.

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